Brd4 Rabbit Monoclonal Antibody

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Catalog Number:MABN86769
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Brd4
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:20-1:50
Molecular Weight:Calculated MW:152 kDa; Observed MW:152 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CAP; MCAP; HUNK1; HUNKI

Applications

WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:20-1:50

Immunogen

A synthetic peptide of human Brd4

Target Background

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Synonyms:CAP; MCAP; HUNK1; HUNKI

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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