Immunological Sciences

Brk Rabbit Monoclonal Antibody

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Catalog Number:MABN87102
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Brk
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:500,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:52 kDa; Observed MW:52 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PTK6

Applications

WB 1:500-1:2000,IHC 1:200-1:500,FC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human Brk

Target Background

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Synonyms:PTK6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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