c-Rel Rabbit Monoclonal Antibody

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Catalog Number:MABN87663
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human c-Rel
Reactivity:Human
Applications:WB 1:500-1:2000,IP 1:10-1:100
Molecular Weight:Calculated MW:69 kDa; Observed MW:78 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:C-Rel

Applications

WB 1:500-1:2000,IP 1:10-1:100

Immunogen

A synthetic peptide of human c-Rel

Target Background

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Synonyms:C-Rel

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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