Immunological Sciences

C1QB (12D10) Rabbit Monoclonal Antibody

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Catalog Number:MABN07721
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human C1QB
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:100
Molecular Weight:27kDa
Purification:Affinity purification
Form:Liquid
Synonyms:C1qb; Complement component 1 q subcomponent B chain;

Applications

WB 1:1000-1:5000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human C1QB

Target Background

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Synonyms:C1qb; Complement component 1 q subcomponent B chain;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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