Immunological Sciences

C3aR Rabbit Polyclonal Antibody

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Catalog Number:ABN07746
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224
Reactivity:Human,Rat,Mouse
Applications:IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R

Applications

IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224

Target Background

C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,

Synonyms:C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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