Immunological Sciences

C4 binding protein (14B18) Rabbit Monoclonal Antibody

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Catalog Number:MABN07750
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human C4 binding protein
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,IP 1:50-1:100
Molecular Weight:28kDa
Purification:Affinity purification
Form:Liquid
Synonyms:C4BP; C4BPB; PRP;

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,IP 1:50-1:100

Immunogen

Recombinant protein of human C4 binding protein

Target Background

Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

Synonyms:C4BP; C4BPB; PRP;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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