Calpain 2 (3O9) Rabbit Monoclonal Antibody

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Catalog Number:MABN07867
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Calpain 2
Reactivity:Human
Applications:WB 1:500-1:2000,FC 1:50-1:100
Molecular Weight:80kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CALP80; Calpain M type; Calpain-2 large subunit; Calpain2; CANP2; CANPL2; CANPml; Capa2; CAPN2; M calpain; mCANP; Millimolar calpain;

Applications

WB 1:500-1:2000,FC 1:50-1:100

Immunogen

A synthetic peptide of human Calpain 2

Target Background

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

Synonyms:CALP80; Calpain M type; Calpain-2 large subunit; Calpain2; CANP2; CANPL2; CANPml; Capa2; CAPN2; M calpain; mCANP; Millimolar calpain;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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