Calponin 2 Rabbit Polyclonal Antibody

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Catalog Number:ABN07872
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CNN2. AA range:121-170
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000
Molecular Weight:33kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human CNN2. AA range:121-170

Target Background

The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,tissue specificity:Heart and smooth muscle.,

Synonyms:CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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