Immunological Sciences

Calponin (6N15) Rabbit Monoclonal Antibody

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Catalog Number:MABN07871
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Calponin 1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:500
Molecular Weight:33kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Calponin-1; Basic calponin; Calponin H1, smooth muscle; CNN1

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:500

Immunogen

A synthetic peptide of human Calponin 1

Target Background

Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated Myosin. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).

Synonyms:Calponin-1; Basic calponin; Calponin H1, smooth muscle; CNN1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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