CaMKII Rabbit Monoclonal Antibody

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Catalog Number:MABN87614
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CaMKII
Reactivity:Human, Mouse, Rat
Applications:WB 1:1000-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:100,FC 1:20-1:100
Molecular Weight:Calculated MW:54 kDa; Observed MW:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CAMKA

Applications

WB 1:1000-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:100,FC 1:20-1:100

Immunogen

A synthetic peptide of human CaMKII

Target Background

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]

Synonyms:CAMKA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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