Immunological Sciences

CAPON Rabbit Monoclonal Antibody

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Catalog Number:MABN03909
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CAPON
Reactivity:Human, Mouse, Rat
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100
Molecular Weight:Calculated MW:56 kDa;Observed MW: 56 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CAPON, KIAA0464,NOS1AP,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein,C-terminal PDZ ligand of neuronal nitric oxide synthase protein,

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100

Immunogen

A synthetic peptide of human CAPON

Target Background

Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862).

Synonyms:CAPON, KIAA0464,NOS1AP,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein,C-terminal PDZ ligand of neuronal nitric oxide synthase protein,

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

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