CAPON Rabbit Monoclonal Antibody

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Catalog Number:MABN86861
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CAPON
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,ICC/IF 1:20-1:50,FC 1:50-1:200
Molecular Weight:Calculated MW:56 kDa; Observed MW:56 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CAPON; 6330408P19Rik

Applications

WB 1:1000-1:5000,ICC/IF 1:20-1:50,FC 1:50-1:200

Immunogen

A synthetic peptide of human CAPON

Target Background

This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009]

Synonyms:CAPON; 6330408P19Rik

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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