Immunological Sciences

Cardiac Troponin I Rabbit Monoclonal Antibody

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Catalog Number:MABN87817
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Cardiac Troponin I
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:24 kDa; Observed MW:28 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

Applications

WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human Cardiac Troponin I

Target Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Synonyms:CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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