Casein Kinase 1 alpha Rabbit Monoclonal Antibody

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Catalog Number:MABN87542
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Casein Kinase 1 alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000
Molecular Weight:Calculated MW:39 kDa; Observed MW:34 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p

Applications

WB 1:500-1:2000

Immunogen

A synthetic peptide of human Casein Kinase 1 alpha

Target Background

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).

Synonyms:CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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