Caspase-1 Rabbit Monoclonal Antibody

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Catalog Number:MABN84656
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Caspase 1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW: 45 kDa ; Observed MW: 45,42,35,12,10 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;;Caspase 1

Applications

WB 1:1000-1:2000,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human Caspase 1

Target Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Synonyms:CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;;Caspase 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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