Caspase-2 Rabbit Monoclonal Antibody

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Catalog Number:MABN87709
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Caspase-2
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:200-1:500,FC 1:200-1:500
Molecular Weight:Calculated MW:51 kDa; Observed MW:48 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57

Applications

WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:200-1:500,FC 1:200-1:500

Immunogen

Recombinant protein of human Caspase-2

Target Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Synonyms:ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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