Caspase 6 Rabbit Monoclonal Antibody

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Catalog Number:MABN01406
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Caspase-6
Reactivity:Human,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 33 kDa; Observed MW: 11,33 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human Caspase-6

Target Background

Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Synonyms:CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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