Immunological Sciences

Caspase-6 Rabbit Monoclonal Antibody

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Catalog Number:MABN21070
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human Caspase-6
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:10000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:33kD;Observed MW:33kD
Purification:Protein A
Form:Liquid
Synonyms:CASP6;MCH2;Caspase-6;CASP-6;Apoptotic protease Mch-2

Applications

WB 1:2000-1:10000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human Caspase-6

Target Background

Cell localization:Cytoplasm . Nucleus ..This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015],

Synonyms:CASP6;MCH2;Caspase-6;CASP-6;Apoptotic protease Mch-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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