Immunological Sciences

Caspase-9 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN21545
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human Caspase-9
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:CalcuLated MW:46kD;Observed MW:40kD
Purification:Protein A
Form:Liquid
Synonyms:CASP9;MCH6;Caspase-9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6

Applications

WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Recombinant protein of human Caspase-9

Target Background

Cell localization:Cytoplasm.This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Synonyms:CASP9;MCH6;Caspase-9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

No documents available.