Immunological Sciences

Cathepsin K Rabbit Monoclonal Antibody

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Catalog Number:MABN86987
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Cathepsin K
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000
Molecular Weight:Calculated MW:37 kDa; Observed MW:37 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000

Immunogen

A synthetic peptide of human Cathepsin K

Target Background

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]

Synonyms:CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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