Immunological Sciences

Caveolin 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN01768
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 20 kDa; Observed MW: 20 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CAV1; CAV; Caveolin-1

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

A synthetic peptide corresponding to target protein

Target Background

Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Synonyms:CAV1; CAV; Caveolin-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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