Immunological Sciences

Caveolin 2 (CAV2)

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Catalog Number:AB-81515
Conjugate:Unconjugated
Size:100μg
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:POLY
Reactivity:Hu
Applications:Western blot: 1:1000 Immunohistochemistry (Paraffin-embedded Section): 1:1000-1:500 Immunofluorescence: 1:200 Immunocytochemistry/Immunofluorescence: 1:200 Flow Cytometry: 1-3μg/1x106
Purification:Aff. Pur.
Form:Liquid

Applications

Western blot: 1:1000 Immunohistochemistry (Paraffin-embedded Section): 1:1000-1:500 Immunofluorescence: 1:200 Immunocytochemistry/Immunofluorescence: 1:200 Flow Cytometry: 1-3μg/1x106

Target Background

Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a majorcomponent of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects andthey differ in their functional interactions with eterotrimeric G proteins. Both of them are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury.

Storage

Store at -20˚C for one year from date of receipt. Avoid repeated freeze-thaw cycles

Buffer

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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