Caveolin-3 (19O1) Rabbit Monoclonal Antibody

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Catalog Number:MABN08023
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Caveolin-3
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:500-1:2000,IP 1:10-1:100
Molecular Weight:17kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CAV3; M-caveolin; Caveolin 3; VIP21;

Applications

WB 1:1000-1:5000,IHC 1:500-1:2000,IP 1:10-1:100

Immunogen

A synthetic peptide of human Caveolin-3

Target Background

Caveolin-3 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564).

Synonyms:CAV3; M-caveolin; Caveolin 3; VIP21;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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