Immunological Sciences

CCL19 (11F3) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN08137
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human MIP-3 beta
Reactivity:Human
Applications:WB 1:500-1:2000
Molecular Weight:11kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CCL 19;CK beta 11;EBI 1 ligand chemokine;ELC;Exodus3;;MIP3 beta;SCYA 19;SCYA19

Applications

WB 1:500-1:2000

Immunogen

A synthetic peptide of human MIP-3 beta

Target Background

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta- arrestin (ARRB1/2) to ACKR4.

Synonyms:CCL 19;CK beta 11;EBI 1 ligand chemokine;ELC;Exodus3;;MIP3 beta;SCYA 19;SCYA19

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.