Immunological Sciences

CCR3 (9I16) Rabbit Monoclonal Antibody

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Catalog Number:MABN08158
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CCR3
Reactivity:Human,Mouse,Rat
Applications:IHC 1:50-1:200
Molecular Weight:41kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3;

Applications

IHC 1:50-1:200

Immunogen

A synthetic peptide of human CCR3

Target Background

Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954).

Synonyms:CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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