Immunological Sciences

CCR7 Rabbit Monoclonal Antibody

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Catalog Number:MABN87677
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CCR7
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:10000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW:43 kDa; Observed MW:43 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7

Applications

WB 1:2000-1:10000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human CCR7

Target Background

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Synonyms:BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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