Immunological Sciences

CD105 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87179
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD105
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:500
Molecular Weight:Calculated MW:71 kDa; Observed MW:95 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:END; HHT1; ORW1

Applications

WB 1:1000-1:5000,IHC 1:200-1:500

Immunogen

A synthetic peptide of human CD105

Target Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Synonyms:END; HHT1; ORW1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.