Immunological Sciences

CD133 (8F2) Mouse Monoclonal Antibody

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Catalog Number:MABN03671
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG2b
Clone:Monoclonal
Immunogen:Recombinant protein of human CD133
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 97 kDa; Observed MW: 133 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human CD133

Target Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms:Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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