CD140a Mouse Monoclonal Antibody

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
| Catalog Number: | MABN82029 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG2a |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human CD140a (AA: extra 179-361) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 6kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | PDGFRA; PDGFR2; PDGFR-2 |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Applications
IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human CD140a (AA: extra 179-361) expressed in E. Coli.


