CD147 (8C17) Rabbit Monoclonal Antibody

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Catalog Number:MABN08215
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD147
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,IF-P 1:50-1:200
Molecular Weight:42kDa
Purification:Affinity purification
Form:Liquid
Synonyms:5A11; 5F7; Basigin; Bsg; CD147; Collagenase stimulatory factor; EMMPRIN; M6 leukocyte activation antigen; Neurothelin; OK blood group antigen; TCSF; Tumor cell derived collagenase stimulatory factor;

Applications

WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,IF-P 1:50-1:200

Immunogen

A synthetic peptide of human CD147

Target Background

Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857).

Synonyms:5A11; 5F7; Basigin; Bsg; CD147; Collagenase stimulatory factor; EMMPRIN; M6 leukocyte activation antigen; Neurothelin; OK blood group antigen; TCSF; Tumor cell derived collagenase stimulatory factor;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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