Immunological Sciences

CD170 Mouse Monoclonal Antibody

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Catalog Number:MABN82192
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2a
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.
Reactivity:Human
Applications:ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:60.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SIGLEC5; OBBP2; CD33L2; OB-BP2; SIGLEC-5

Applications

ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Target Background

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Synonyms:SIGLEC5; OBBP2; CD33L2; OB-BP2; SIGLEC-5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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