Immunological Sciences

CD20 Mouse Monoclonal Antibody

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Catalog Number:MABN80615
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG
Clone:Monoclonal
Immunogen:Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.
Reactivity:Human
Applications:IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000
Purification:Affinity Purification
Form:Liquid
Synonyms:B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1

Applications

IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.

Target Background

CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.

Synonyms:B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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