Immunological Sciences

CD215 Mouse Monoclonal Antibody

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Catalog Number:MABN82286
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD215 (AA: extra 31-205) expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:28.2kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IL15RA

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human CD215 (AA: extra 31-205) expressed in E. Coli.

Target Background

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]

Synonyms:IL15RA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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