Immunological Sciences

CD247 Mouse Monoclonal Antibody

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Catalog Number:MABN80825
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD247 expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:18kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247

Applications

IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD247 expressed in E. Coli.

Target Background

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms:T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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