Immunological Sciences

CD26 Rabbit Monoclonal Antibody

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Catalog Number:MABN86863
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse CD26
Reactivity:Mouse
Applications:WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:87 kDa; Observed MW:120 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Cd26; THAM; Dpp-4

Applications

WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of mouse CD26

Target Background

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM.

Synonyms:Cd26; THAM; Dpp-4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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