Immunological Sciences

CD27 Rabbit Monoclonal Antibody

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Catalog Number:MABN87116
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD27
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:200-1:500,FC 1:100-1:500
Molecular Weight:Calculated MW:29 kDa; Observed MW:49 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:T14; S152; Tp55; TNFRSF7; S152. LPFS2

Applications

WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:200-1:500,FC 1:100-1:500

Immunogen

A synthetic peptide of human CD27

Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Synonyms:T14; S152; Tp55; TNFRSF7; S152. LPFS2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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