Immunological Sciences

CD275 Mouse Monoclonal Antibody

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Catalog Number:MABN82214
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD275 (AA: extra 19-256) expressed in E. Coli.
Reactivity:Human
Applications:ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:33.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ICOSLG; B7H2; GL50; B7-H2; B7RP1; ICOSL; LICOS; B7RP-1; ICOS-L

Applications

ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD275 (AA: extra 19-256) expressed in E. Coli.

Target Background

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

Synonyms:ICOSLG; B7H2; GL50; B7-H2; B7RP1; ICOSL; LICOS; B7RP-1; ICOS-L

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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