Immunological Sciences

CD28 (phospho Tyr218) Rabbit Polyclonal Antibody

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Catalog Number:ABN04397
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CD28 around the phosphorylation site of Tyr218. AA range:171-220
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:45kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CD28; T-cell-specific surface glycoprotein CD28; TP44; CD antigen CD28

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human CD28 around the phosphorylation site of Tyr218. AA range:171-220

Target Background

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011],function:Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.,online information:CD28 entry,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70.,tissue specificity:Expressed in T-cells and plasma cells, but not in less mature B-cells.,

Synonyms:CD28; T-cell-specific surface glycoprotein CD28; TP44; CD antigen CD28

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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