CD30 Mouse Monoclonal Antibody

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Catalog Number:MABN82838
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD30 (AA: 416-595) expressed in E. Coli.
Reactivity:Human, Mouse
Applications:WB 1:500-1:2000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:63.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Ki-1; D1S166E,TNFRSF8

Applications

WB 1:500-1:2000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD30 (AA: 416-595) expressed in E. Coli.

Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Synonyms:Ki-1; D1S166E,TNFRSF8

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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