Immunological Sciences

CD300b Rabbit Polyclonal Antibody

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Catalog Number:ABN08340
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthetic peptide from human protein at AA range: 61-110
Reactivity:Human,Rat,Mouse
Applications:IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:CMRF35-like molecule 7 (CLM-7;CD300 antigen-like family member B;CMRF35-A2;Immune receptor expressed on myeloid cells 3;IREM-3;Leukocyte mono-Ig-like receptor 5;Triggering receptor expressed on myeloid cells 5;TREM-5;CD antigen CD300b)

Applications

IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

Immunogen

Synthetic peptide from human protein at AA range: 61-110

Target Background

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008],function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2.,PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.,tissue specificity:Expressed exclusively in myeloid lineages.,

Synonyms:CMRF35-like molecule 7 (CLM-7;CD300 antigen-like family member B;CMRF35-A2;Immune receptor expressed on myeloid cells 3;IREM-3;Leukocyte mono-Ig-like receptor 5;Triggering receptor expressed on myeloid cells 5;TREM-5;CD antigen CD300b)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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