CD31 / PECAM-1 (Endothelial Cell Marker) Mouse Monoclonal Antibody

Formalin-fixed, paraffin-embedded tonsil stained with CD31; Clone JC/70A.

Formalin-fixed, paraffin-embedded tonsil stained with CD31; Clone JC/70A.

Catalog Number:MAB-94774
Conjugate:Unconjugated
Size:250 ul
Concentration:250ug/ml
Host:Mouse
Isotype:IgG1, Kappa
Clone:JC/70A
Immunogen:Membrane preparation of a spleen from a patient with hairy cell leukemia.
Reactivity:Human
Applications:Immunohistochemistry (Frozen and Formalin-fixed): 1:500-1:1000 Flow Cytometry: 1-2μg/million cells Immunofluorescence: 1:500-1:1000 Western Blotting: 1:500-1:1000 Immunoprecipitation: 1:500-1:1000 protein lysate
Molecular Weight:~100kDa (endothelium) and ~130kDa (platelets)
Form:Liquid
Synonyms:EndoCAM; PECA1; Platelet Endothelial Cell Adhesion Molecule 1; GPIIA'

Applications

Immunohistochemistry (Frozen and Formalin-fixed): 1:500-1:1000 Flow Cytometry: 1-2μg/million cells Immunofluorescence: 1:500-1:1000 Western Blotting: 1:500-1:1000 Immunoprecipitation: 1:500-1:1000 protein lysate

Immunogen

Membrane preparation of a spleen from a patient with hairy cell leukemia.

Target Background

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially be a predictor of tumor recurrence.

Synonyms:EndoCAM; PECA1; Platelet Endothelial Cell Adhesion Molecule 1; GPIIA'

Storage

Store at 2~8℃, Avoid freeze / thaw cycles

Buffer

250μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.

Formalin-fixed, paraffin-embedded tonsil stained with CD31; Clone JC/70A.

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