CD338 Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
| Catalog Number: | MABN82605 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG2b |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli. |
| Reactivity: | Human, Mouse |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 75kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; ABCG2; GOUT1; MXR-1; CDw338; UAQTL1; EST157481 |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications
WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli.
