Immunological Sciences

CD3E Mouse Monoclonal Antibody

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Catalog Number:MABN80838
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of CD3E expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:23kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:T3E; TCRE; FLJ18683; CD3E

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of CD3E expressed in E. Coli.

Target Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Synonyms:T3E; TCRE; FLJ18683; CD3E

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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