Immunological Sciences

CD49B Mouse Monoclonal Antibody

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Catalog Number:MABN82060
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.
Reactivity:Human
Applications:ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:129.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2

Applications

ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.

Target Background

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Synonyms:ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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