Immunological Sciences

CD55 Rabbit Monoclonal Antibody

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Catalog Number:MABN01797
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human CD55
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 41 kDa; Observed MW: 78 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD55; CR; DAF; Complement decay-accelerating factor; CD55

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human CD55

Target Background

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Synonyms:CD55; CR; DAF; Complement decay-accelerating factor; CD55

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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