Immunological Sciences

CD6 Rabbit Polyclonal Antibody

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Catalog Number:ABN08425
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CD6. AA range:250-299
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:73kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CD6; T-cell differentiation antigen CD6; T12; TP120; CD antigen CD6

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human CD6. AA range:250-299

Target Background

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],function:Involved in cell adhesion. Binds to CD166.,PTM:After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.,PTM:Contains intrachain disulfide bond(s).,similarity:Contains 3 SRCR domains.,tissue specificity:Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.,

Synonyms:CD6; T-cell differentiation antigen CD6; T12; TP120; CD antigen CD6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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