Immunological Sciences

CD68 Mouse Monoclonal Antibody

Flow cytometry intracellular staining pattern of human peripheral blood stained using anti-human CD68 (Y1/82A) purified antibody (concentration in sample 2 μg/ml) GAM FITC.

Flow cytometry intracellular staining pattern of human peripheral blood stained using anti-human CD68 (Y1/82A) purified antibody (concentration in sample 2 μg/ml) GAM FITC.

Catalog Number:MAB-94308
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Y1/82A
Immunogen:Lysosomal contents of lung macrophages
Reactivity:Human
Applications:Flow cytometry: Recommended dilution: 2-6 μg/ml. Extracellular and intracellular staining
Molecular Weight:110 kDa
Purification:Purified by protein-A affinity chromatography
Form:Liquid
Synonyms:GP110, LAMP4, SCARD1

Applications

Flow cytometry: Recommended dilution: 2-6 μg/ml. Extracellular and intracellular staining

Immunogen

Lysosomal contents of lung macrophages

Target Background

CD68 (also known as LAMP4 or SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).

Synonyms:GP110, LAMP4, SCARD1

Storage

Store at 2-8°C. Do not freeze.

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Flow cytometry intracellular staining pattern of human peripheral blood stained using anti-human CD68 (Y1/82A) purified antibody (concentration in sample 2 μg/ml) GAM FITC.

Separation of human monocytes (red-filled) from CD68 negative lymphocytes (black-dashed) in flow cytometry analysis (intracellular staining) of human peripheral whole blood stained using anti-human CD68 (Y1/82A) purified antibody (concentration in sample 2 μg/ml) GAM FITC.

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