CD68 Rabbit Polyclonal Antibody
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CD68 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
| Catalog Number: | ABN08435 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml . The concentration of this product may be batch dependent. |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of mouse CD68 |
| Reactivity: | Mouse,Rat |
| Applications: | IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000 |
| Molecular Weight: | 37kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
| Synonyms: | CD68 antigen; CD68 molecule; Gp110; LAMP4; Macrophage antigen CD68 (microsialin); Macrosialin; SCARD1; Scavenger receptor class D member 1 |
CD68 belongs to a family of acidic, highly glycosylated lysosomal glycoproteins (LGPs) that includes lamp-1 and lamp-2. Play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Applications
IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Immunogen
A synthetic peptide of mouse CD68
