Immunological Sciences

CD74 Rabbit Monoclonal Antibody

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Catalog Number:MABN86464
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human CD74
Reactivity:Human
Applications:IHC 1:200-1:500
Molecular Weight:Calculated MW:34 kDa; Observed MW:34 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:II; p33; DHLAG; HLADG; Ia-GAMMA

Applications

IHC 1:200-1:500

Immunogen

A synthetic peptide of human CD74

Target Background

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Synonyms:II; p33; DHLAG; HLADG; Ia-GAMMA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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