Immunological Sciences

CD82 Mouse Monoclonal Antibody

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Catalog Number:MABN82973
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2a
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human CD82 (AA: extra 111-228) expressed in E. Coli.
Reactivity:Human, Mouse
Applications:IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:29.6kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27

Applications

IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human CD82 (AA: extra 111-228) expressed in E. Coli.

Target Background

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms:R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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